A digestive-enzyme capsule matches standard therapy for functional dyspepsia in older adults.
Wenhui Liu, Lishu Xu, Xiling Chen, et al.
In a multicenter real-world study of 175 older adults with postprandial distress syndrome, pancreatin enteric-coated capsules relieved symptoms as effectively as the standard prokinetic itopride, whether used alone or in combination, with benefits appearing from the first day of treatment. Anxiety and depression scores also improved similarly across all three treatment groups, and no treatment-related adverse events were reported. The authors conclude pancreatin monotherapy is a safe, effective alternative for older patients when prokinetic side effects are a concern.
- The question: Can a digestive enzyme capsule match a standard prokinetic for older patients?
- The study: A multicenter real-world study followed 175 older adults with postprandial distress syndrome.
- The finding: Pancreatin enteric-coated capsules relieved symptoms as effectively as itopride, alone or combined, with benefit from the first day of treatment.
- The nuance: Anxiety and depression scores improved similarly across all three groups, and no treatment-related adverse events were reported.
Takeaway: pancreatin monotherapy is a safe, effective alternative for older patients when prokinetic side effects are a concern.
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