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Visual abstract — The global, regional, and national patterns of change in the burden of gastroesophageal reflux disease, 1990-2021: An analysis of the global burden of disease study 2021 and forecast to 2036
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Original ArticleVisual abstract19 December 2025

The global, regional, and national patterns of change in the burden of gastroesophageal reflux disease, 1990-2021: An analysis of the global burden of disease study 2021 and forecast to 2036

GERD's global burden has nearly doubled since 1990, with youth and low-resource regions hit hardest.

Saudi Journal of GastroenterologySaudi J Gastroenterol. 2026; 32(2); pp. 150-162

Baoqing Liu, Shengwei Ji, Wangxin Zhou, et al.

SGA Briefing

Drawing on Global Burden of Disease 2021 data, this study tracks a roughly 80% rise in gastroesophageal reflux disease cases, incidence, and disability-adjusted life years worldwide since 1990. The burden is shifting toward younger adults and widening between high- and low-resource countries, and projections point to continued growth through 2036. The authors call for targeted resource allocation, particularly in lower socio-demographic-index regions.

57-second video summary
What this video shows
  1. The question: Is reflux disease actually getting worse worldwide?
  2. The study: Drawing on Global Burden of Disease 2021 data, researchers tracked GERD cases, incidence, and disability-adjusted life years from 1990 onward.
  3. The finding: GERD's global burden has risen by roughly 80% since 1990, and is projected to keep growing through 2036.
  4. The nuance: The burden is shifting toward younger adults, and the gap is widening between high- and low-resource countries.

Takeaway: GERD's burden keeps climbing worldwide, and the authors call for targeted resource allocation, especially in lower socio-demographic-index regions.

Narrated (standard AI voice, not a cloned voice) with burned-in captions matching the narration word-for-word — safe to watch muted. Built from this article’s SGA Briefing only.

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